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Objective To explore the feasibility of open visiting among mothers' of very-low-birth-weight(VLBW) infants and observe effects.Methods Totally 74 eligible VLBW infants were recruited,those who were visited and cared daily by mothers were assigned into the experimental group(n=36) and those who were not visited by mothers were assigned into the control group(n=38).The experimental group received open visiting as well as individualized developmental nursing care,and the control group only received individualized developmental nursing care.Relevant regulations and procedures were designed,and clinical pathways of mothers' involvement in nursing care were developed and implemented.Incidence of infection,time to reach full oral feeding,weight gaining during hospitalization,rate of breast-feeding during hospitalization and 30 days after discharge,hospitalization time and rate of readmission 30 days after discharge were recorded and compared.Results There was no significant difference in incidence of infection between two groups (P＞0.05).Time to reach full oral feeding in the experimental group was earlier than that of the control group,weight gaining during hospitalization in the experimental group was faster than that of the control group,rate of breast-feeding 30 days after discharge was higher in the experimental group,and the differences were significant (P＜0.05).Hospitalization time in the experimental group was shorter than that of the control group,rate of readmission 30 days after discharge in the experimental group was lower,and the differences were significant (P＜0.05).Conclusion Mother's open visiting for VLBW infants in NICU does not increase the incidence of infection,but can shorten time to reach full oral feeding,promote weight gaining,increase rate of breast-feeding 30 days after discharge,reduce hospitalization time,and decrease rate of readmission 30 days after discharge.
ABSTRACT
<p><b>BACKGROUND</b>Reports on mood regulating circuit (MRC) indicated different activities between depressed patients and healthy controls. The functional networks based on MRC have not been described in major depression disorder (MDD). Both the anterior cingulate cortex (ACC) and thalamus are all the key regions of MRC. This study was to investigate the two functional networks related to ACC and thalamus in MDD.</p><p><b>METHODS</b>Sixteen patients with MDD on first episode which never got any medication and sixteen matched health controls were scanned by 3.0 T functional magnetic resonance imaging (fMRI) during resting-state. The pregenual anterior cingulate cortex (pgACC) was used as seed region to construct the functional network by cortex section. The thalamus was used as seed region to construct the functional network by limbic section. Paired-t tests between-groups were performed for the seed-target correlations based on the individual fisher z-transformed correlation maps by SPM2.</p><p><b>RESULTS</b>Depressed subjects exhibited significantly great functional connectivity (FC) between pgACC and the parahippocampus gyrus in one cluster (size 923) including left parahippocampus gyrus (-21, -49, 7), left parietal lobe (-3, -46, 52) and left frontal lobe (-27, -46, 28). The one cluster (size 962) of increased FC on thalamus network overlapped the precuneus near to right parietal lobe (9, -52, 46) and right cingulate gyrus (15, -43, 43) in health controls.</p><p><b>CONCLUSIONS</b>Abnormal functional networks exist in earlier manifestation of MDD related to MRC by both cortex and limbic sections. The increased functional connectivity of pgACC and decreased functional connectivity of thalamus is mainly involved in bias mood processing and cognition.</p>
Subject(s)
Adult , Female , Humans , Male , Depressive Disorder, Major , Gyrus Cinguli , Magnetic Resonance Imaging , Methods , ThalamusABSTRACT
Objective To Analyze the imaging characteristics of intraparenchymal schwannoma and the related pathology,in order to improve the accuracy of diagnosis and be in favor of the clinics and the prognosis.Methods Four cases were confirmed to be intraparenchymal schwannoma by pathological and immunohistochemistry examination.One case was examined with precontrast and enhanced CT scanning,one with unenhanced MRI scanning,two with unenhanced and enhanced CT and MRI scanning.Their images were retrospectively analyzed.Results Of the four cases,three patients were less than 30 years old,with tumors located supratentorially.Cysts were found in all cases,with nodules on the wall in 3 cases.The nodules were enhanced markedly in two cases and moderately in one ease.In addition,calcification was detected in one case and prominent peritumoral edema existed in 1 case.The picture of the pathology demonstrated Antoni type A and Antoni type B.Immunostaining showed intense immunoreactivity for S-100 protein and Vim and negative immunoreactivity for GFAP and EMA.Conclusions Intraparenchymal schwannoma mostly occurred in juvenile,which located supratentorially in most cases.The presence of a cyst and peritumoral edema together with the tumor appears to be characteristic of intraparenchymal schwannoma.Calcification or the enhanced nodule is the helpful sign for the diagnosis.Combining the imaging findings with the pathology and immunohistochemistry results can gain the accurate diagnosis.